Research

Selected Publications

 

Szuktak, A., Lee, H. H., Quintero, J. M., Aldao, A., Fresco, D. M., & Mennin, D. S. (in press). Changes in phasic heart rate variability predict clinical outcomes following emotion regulation therapy for generalized anxiety disorder and comorbid depression. Behavior Therapy.

Applebaum, A. J., Jacobs, J. M., Fresco, D. M., Hoyt, M. A., Schofield, E., Loschiavo, M. J., O'Toole, M. S., Dunderdale, L. E., & Mennin, D. S. (2026). Randomized controlled trial of emotion regulation therapy versus cognitive behavioral therapy to address distress in cancer caregivers. Annals of Behavioral Medicine, 60(1).

Szkutak, A., Lawrence, O., Clayton, M. E., Heimberg, R. G., Fresco, D. M., & Mennin, D. S. (2025). Convergence of therapist case conceptualizations and patient ratings of targeted mechanisms in predicting treatment outcomes. Cognitive Therapy & Research.

Karim, H. T., Gross, J. J., Mennin, D., Gerlach, A., Tudorascu, D. L., Butters, M. A., Ladouceur, C., & Andreescu, C. (2025). Older and wiser? The neural correlates of worry induction and reappraisal in older adults. Neuropsychopharmacology, 50(13), 1949–1958.

Mikkelsen, M. B., Elkjær, E., Mennin, D. S., Michalak, J., & O'Toole, M. S. (2025). The power of posing: Do body display instructions have an impact on behavior in daily life? Brain and Behavior.

Renna, M. E., Spaeth, P. E., Behringer, K. F., Qina'au, J., Clayton, M., & Mennin, D. S. (2025). A pilot study examining differential relationships between inflammation and emotion dysregulation across young and middle adulthood. Health Psychology, 44(7), 708–714.

Renna, M. E., Spaeth, P. E., Clayton, M., & Mennin, D. S. (2025). Emotional reactivity and regulation: Associations with heart rate variability during experimental worry and relaxation inductions. Journal of Emotion and Psychopathology, 1(2), 478–488.

Szkutak, A., Anene, E., Mennin, D. S., & Fresco, D. M. (2025). Emotion regulation therapy (ERT) I: History and theoretical frameworks. In W. Li, G. Griffith, S. Shapiro, & Z. Zhu (Eds.), The Palgrave handbook of third-wave psychotherapies (pp. 247–268). Palgrave Macmillan.

Clayton, M., Hernandez, M., Mennin, D. S., & Fresco, D. M. (2025). Emotion regulation therapy (ERT) II: Treatment mechanisms and components. In W. Li, G. Griffith, S. Shapiro, & Z. Zhu (Eds.), The Palgrave handbook of third-wave psychotherapies (pp. 269–292). Palgrave Macmillan.

Spaeth, P., Renna, M., Skytte O'Toole, M., Mennin, D. S., & Fresco, D. M. (2025). Emotion regulation therapy III: Foundations and frontiers in investigating efficacy and mechanism. In W. Li, G. Griffith, S. Shapiro, & Z. Zhu (Eds.), The Palgrave handbook of third-wave psychotherapies (pp. 293–312). Palgrave Macmillan.

Mennin, D. S., & Fresco, D. M. (2024). Emotion regulation therapy. In J. J. Gross & B. Ford (Eds.), Handbook of emotion regulation (3rd ed., pp. 383–390). Guilford Press.

Szkutak, A., Renna, M. E., Quintero, J. M., & Mennin, D. S. (2024). Gastric myoelectrical associations with autonomic and central nervous system activity during state negative emotionality and perseverative negative thinking: A two-study investigation. Brain, Behavior, and Immunity Integrative, 6, Article 100062.

Clayton, M., Young, E., Zhu, S., Renna, M. E., & Mennin, D. S. (2024). The Behavioral Dysregulation Scale: Initial psychometric properties of a self-report measure of behavioral emotion dysregulation. Personality and Individual Differences, 222, 112579.

Renna, M. E., Spaeth, P. E., Quintero, J. M., O'Toole, M. S., Sandman, C. F., Fresco, D. M., & Mennin, D. S. (2023). A randomized controlled trial comparing two doses of emotion regulation therapy: Preliminary evidence that gains in attentional and metacognitive regulation reduce worry, rumination, and distress. Behaviour Research and Therapy, 170, 104420.

Clayton, M., Renna, M. E., Klemanski, D. H., Kerns, C., McLaughlin, K. A., & Mennin, D. S. (2023). The impact of emotion regulation on the relationship between momentary negative affect and end-of-day worry and rumination. Cognitive Therapy and Research, 47, 94–108.

Clayton, M., Renna, M. E., Weingast, L., Panjwani, A. A., Spaeth, P. E., Heimberg, R. G., Fresco, D. M., & Mennin, D. S. (2023). The impact of emotion regulation improvements on intolerance of uncertainty during emotion regulation therapy. Journal of Emotion and Psychopathology, 1, 273–288.

Gruber, J., Hagerty, S., Mennin, D. S., & Gross, J. J. (2022). Mind the gap? Emotion regulation ability and achievement in psychological disorders. Journal of Emotion and Psychopathology, 1, 63–69.

Cho, H., Myruski, S., Denefrio, S., Mennin, D. S., & Dennis-Tiwary, T. A. (2022). Associations between GAD symptom severity and error monitoring depend on neural quenching variability. Motivation and Emotion, 46, 254–263.

Quintero, J. M., Mennin, D. S., Mayville, E., Heimberg, R. G., & Fresco, D. M. (2022). Implicit approach and avoidance motivational changes in GAD patients treated with emotion regulation therapy. Journal of Behavioral and Cognitive Therapy, 32, 151–156.

Schettino, M., Ghezzi, V., Ang, Y-S., Duda, J. M., Fagioli, S., Mennin, D. S., Pizzagalli, D. A., & Ottaviani, C. (2021). Perseverative cognition in the positive valence systems: An experimental and ecological investigation. Brain Sciences, 11(5), 585.

O’Toole, M. S., Mennin, D. S., Zachariae, R., Applebaum, A., Fresco, D. M., & Zachariae. (2021). Moderators and mediators of emotion regulation therapy for psychologically distressed caregivers of cancer patients. Acta Oncologica, 60(8), 992-999.

Mikkelsen, M. B., Elkjær, E., Mennin, D. S., Fresco, D. M., Zachariae, R., Applebaum, A., & O’Toole, M. S. (2021). The impact of emotion regulation therapy on emotion differentiation in psychologically distressed caregivers of cancer patients. Anxiety, Stress, & Coping, 34(4) 479-485.

Renna, M.E., O’Toole, M.S., Fresco, D.M., Heimberg, R.G., Mennin, D.S. (2021). From psychological to physical health: Exploring temporal precedence throughout emotion regulation therapy. Journal of Anxiety Disorders, 80, 102403.

Abasi, I., Pourshahbaz, A., Mohammadkhani, P., Dolatshahi, B., Moradveisi, L., & Mennin, D. S. (2021). Emotion regulation therapy for social anxiety disorder: a single case series study. Behavioural and Cognitive Psychotherapy, 49, 658-672

Renna, M. E., Hoyt, M. A., Ottiavani, C., Mennin, D. S. (2020). An experimental examination of worry and relaxation on autonomic, endocrine, and immunological processes. Psychoneuroimmunology, 104870.

Elkjær, E., Mikkelsen, M. B., Michalak, J., Mennin, D. S. & O’Toole, M. S. (2020). Expansive and contractive postures and movement: A systematic review and meta-analysis of the effect of motor displays on affective and behavioral responses. Perspectives in Psychological Science, 1-29.

Renna, M. E., Fresco, D. M., & Mennin, D. S. (2020). Emotion regulation therapy and its potential role in the treatment of chronic stress related pathology across disorders. Chronic Stress, 4, 1-10.

Cludius, B., Mennin, D. S., & Ehring, T. (2020). Emotion regulation as a transdiagnostic process. In J. Gross & K. McRae (Eds), Fundamental Questions in Emotion Regulation (Special Issue), Emotion, 20,  37-42.

O’Toole, M. S., Mennin, D. S., Applebaum, A., Weber, B., Rose, H., Fresco, D. M., & Zachariae, R. (2020). A randomized controlled trial of emotion regulation therapy for psychologically distressed caregivers of cancer patients. JNCI Spectrum, 4, 1-9.

O’Toole, M. S., *Renna, M. E., Mennin, D. S., & Fresco, D. M. (2019). Changes in decentering and reappraisal temporally precede symptom reduction during emotion regulation therapy for generalized anxiety disorder with and without co-occurring depression. Behavior Therapy, 1042-1052.

O’Toole, M. S., & *Renna, M. E., Elkjær, E, Mikkelsen, M. B., & Mennin, D. S., (2019). A systematic review and meta-analysis of the association between complexity of emotion experience and behavioral adaptation. Emotion Review, 12, 23-38.

Wu, M., Mennin, D. S., Ly, M., Karim, H., Tudorascu, D., Aizenstein, H. J., & Andreescu, C. (2019). When worry may be good for you: Worry severity and limbic-prefrontal functional connectivity in late-life generalized anxiety disorder. Journal of Affective Disorders, 650-657.

Denefrio, S., Myruski, S., Mennin, D. S., & Dennis-Tiwary, T. A. (2019). When neutral is not neutral: Neurophysiological evidence for reduced discrimination between threat and non-threat in generalized anxiety disorder. Motivation and Emotion, 43, 325-338.

Panjwani, A. A., O’Toole, M. S., Applebaum, A., Fresco, D. M., & Mennin, D. S. (2019), Emotion Regulation Therapy for cancer caregivers: Targeting mechanisms of distress (pp. 219-236). In A. Applebaum (Ed)., Cancer Caregivers. New York: Oxford University Press.

Scult, M., Fresco, D. M., Gunning, F., *Seeley, S., *García-Lesy, E., Liston, C., & Mennin, D. S. (2019). Changes in functional connectivity following treatment with Emotion Regulation Therapy. Frontiers in Behavioral Neuroscience (Research Topic, Neurobiological Models of Psychotherapy), 13, Article 10, 1-14.

Fresco, D M., & Mennin, D. S., (2019).  All together now: Utilizing common functional change principles to unify cognitive behavioral and mindfulness-based therapies. Current Opinion in Psychology, 28, 65-70.

Mennin, D. S. (2018). Identifying efficacious treatment elements for refractory conditions such as body dysmorphic disorder. JAMA Psychiatry, 76, 357-358.

Mennin, D.S., Fresco, D.M., Heimberg, R.G., & O’Toole, M. (2018). A randomized control trial of Emotion Regulation Therapy for generalized anxiety disorder without and without co-occurring depression. Journal of Consulting and Clinical Psychology, 86, 268-281. [Ranked in the top 10 of downloaded articles in 2018 from 4000+ articles in 89 APA journals, APA Monitor, Dec 2018, p. 39]

Applebaum, A., Panjwani, A. A., Buda, K., O’Toole, M. S., Hoyt, M., Garcia, A., Fresco, D. M., & Mennin, D. S. (2018). Emotion regulation therapy for cancer caregivers: A mechanism-targeted approach to addressing caregiver distress. Translational Behavioral Medicine.

O’Toole, M. S., Bovbjerg, D. H., *Renna, M. E., Lekander, M., Mennin, D. S., & Zachariae, R. (2018). Effects of psychological interventions on systemic levels of inflammatory biomarkers in humans: A systematic review and meta-analysis. Brain, Behavior, & Immunity, 74, 68-78.

Renna, M.E., O’Toole, M.S., Spaeth, P.E., Lekander, M, Mennin, D.S. (2018). The association between anxiety, traumatic stress, and obsessive-compulsive disorders and chronic inflammation: A systematic review and meta-analysis. Depression & Anxiety, 35, 1081-1094.

Renna, M. E., *Quintero, J. M., Soffer, A., Pino, M., Ader, L., Fresco, D. M., & Mennin, D.S. (2018). A pilot study of Emotion Regulation Therapy for generalized anxiety and depression from a diverse sample of young adults. Behavior Therapy, 49, 403-418.

Renna, M. E., Seeley, S. H., Etkin, A., Heimberg, R. G., Fresco, D. M., & Mennin, D. S. (2018). Increased attention flexibility from Emotion Regulation Therapy for generalized anxiety disorder. Cognitive Therapy and Research, 42, 121-142.

Renna, M.E., Chin, S., Seeley, S.H., Fresco, D.M., Heimberg, R.G., Mennin, D.S. (2018). The use of the mirror tracing persistence task as a measure of distress tolerance in generalized anxiety disorder. Journal of Rational-Emotive & Cognitive-Behavior Therapy, 36, 80-88.

Thompson, R. J., Kogan, A., Insel, P., Mennin, D., Gotlib, I. H., & Gruber, J. (2017). Positive and negative affective forecasting in remitted individuals with bipolar I disorder, and major depressive disorder, and healthy controls. Cognitive Therapy and Research, 41, 673-685.

O’Toole, M. S., Zachariae, R., & Mennin, D. S. (2017). Social anxiety and emotion regulation flexibility: Considering emotion intensity and type as contextual factors. Anxiety, Stress, & Coping, 30, 716-724.

Fresco, D. M., Roy, A. K., Adelsberg, S., Seeley, S., García-Lesy, E., Liston, C., & Mennin, D. S. (2017). Distinct functional connectivities predict clinical response with Emotion Regulation Therapy. Frontiers in Human Neuroscience (Research Topic, Can't Get You Out of My Head: Brain-Body Interactions in Perseverative Cognition), 11, Article 86, 1-13.

Renna, M. E., Quintero, J. M., Mennin, D. S., & Fresco, D.M. (2017). Emotion Regulation Therapy: A mechanism-targeted treatment for disorders of distress. Frontiers in Psychology (Research Topic on Emotion Science, Advances in Emotion Regulation: from neuroscience to psychotherapy), 8, Article 98, 1-14.

O’Toole, M. S., Zachariae, R., Renna, M., Mennin, D. S., & Applebaum, A. (2017). Cognitive behavioral therapies for informal caregivers of patients with cancer and cancer survivors: A systematic review and meta-analysis. Psycho-Oncology, 26, 428-437.

Plate, A. J., Aldao, A., Quintero, J. M., & Mennin, D. S. (2016). Interactions between reappraisal and emotional nonacceptance in psychopathology: Examining disability and depression symptoms in generalized anxiety disorder. Cognitive Therapy and Research, 40, 733-746.

Wichelns, G. A., Renna, M. E., & Mennin, D. S. (2016). Preliminary validation of subjective anchor scales for worry and rumination. Cognitive Therapy and Research, 40, 645–660.

Jensen, D., Cohen, J. N., Mennin, D. S., Fresco, D M., & Heimberg, R. G. (2016). Clarifying the unique associations among intolerance of uncertainty, anxiety, and depression. Cognitive Behaviour Therapy, 45, 431-444.

Seeley, S. H., Mennin, D.S., Aldao, A., McLaughlin, K. A., Rottenberg, J., & Fresco, D. M. (2016). Impact of comorbid depressive disorders on subjective and physiological responses to emotion in generalized anxiety disorder. Cognitive Therapy and Research, 40, 290-303.

Mennin, D. S., Fresco, D. M., Heimberg, R. G., & Ritter, M. (2015). An open trial of Emotion Regulation Therapy for generalized anxiety disorder and co-occurring depression. Depression & Anxiety, 32, 614-623.

Mennin, D. S., & Fresco, D. M. (2015). Advancing emotion regulation perspectives on psychopathology: The challenge of distress disorders (Commentary on Gross, 2015). Psychological Inquiry, 26, 80-92.

Seeley, S. H., Garcia, E., & Mennin, D. S. (2015). Recent advances in laboratory assessment of emotion regulation. Current Opinions in Psychology, 3, 58-63.

Andreescu  C., Mennin, D. S., Tudorascu, D., Sheu, L. K., Walker, S., Banihashemi, L., & Aizenstein, H. (2015). The many faces of anxiety - neurobiological correlates of anxiety phenotypes. Psychiatry Research: Neuroimaging, 234, 96-105.

Gruber, J., Mennin, D., Fields, A., Purcell, A. L., & Murray, G. (2015). Heart rate variability as a potential indicator of positive valence system disturbance: A proof of concept investigation. International Journal of Psychophysiology, 98, 240-248.